ISSN: 1305-3876
Dil: Türkçe
Hakkında: Özel sayılar şeklinde yayınlanır.
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Chemical Traumas And Emergency Therapy Approachs
Dr. Altuğ ÇETİNKAYA,a Dr. Yonca AYDIN AKOVAa
aGöz Hastalıkları AD, Başkent Üniversitesi Tıp Fakültesi, ANKARA
Chemical injuries can cause severe damage to the entire anterior segment of the eye and result in permanent visual loss. The severity of the damage depends on the duration of tissue interaction as well as the amount, concentration and pH of the agent. The acid injuries usually result in barrier formation by denaturizing proteins, thus they do not penetrate to deeper levels. Alkali injuries however usually penetrate deeply by causing profound necrosis in the tissues.
The immediate measures to be taken after exposure to acid or alkali agents are prolonged surface irrigation and removal of any particle from the ocular surface. These measures should be followed by the evaluation of the limbal stem cell population, and grading of the damage should be done for prognosis. The rationale of the early treatment are providing reepithelization, avoiding ulceration, suppressing inflammation, and aiding in corneal healing response. Early surgery may be necessary if the entire limbal stem cells are destroyed. The surgical procedures involve removal of the necrotic conjunctiva, reinstitution of limbal vascularity, or limbal transplantation. These methods are preferred for prevention of ulceration and pannus formation. Penetrating keratoplasty is the restorative surgery for visual rehabilitation in the late term.Keywords: Acid, alkaline, chemical traumaTurkiye Klinikleri J Surg Med Sci 2006, 2(42):26-31
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