ISSN: 1305-3876
Dil: Türkçe
Hakkında: Özel sayılar şeklinde yayınlanır.
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Intracranial Metastasis And Increased Icp
Dr. Cem ÖNALa Dr. Enis ÖZYARb
aRadyasyon Onkolojisi AD, Başkent Üniversitesi Tıp Fakültesi, Adana Eğitim ve Araştırma Hastanesi, ADANAbRadyasyon Onkolojisi AD, Hacettepe Üniversitesi Tıp Fakültesi, ANKARA
Brain metastases are among the most featured complications of cancer, because they often cause profound neurologic symptoms that severely impair quality of life. The neorologic symptoms usually occurs as a result of incresed intracranial pressure (ICP). Approximately 10-30% of patients with cancer develop brain metastases. Although usually appearing late in the course of the disease, the brain metastasis may be present before the primary cancer has been identified and may present as a single lesion or as multiple lesions. The diagnostic and therapeutic approach depends on the number and location of brain lesions and the stage of the cancer. The treatment of choice was assessed according to the prognostic factors developed by Radiation Therapy Oncology Group (RTOG). The method of Recursive Partitioning Analysis (RPA) provides a decision tree in which each branch is based on election of prognostic factor that causes the largest difference in outcome. However, appropriate treatment can improve both the quality and duration of the patient's life. Treatment must be directed not only at the brain metastasis (definitive care), but also at a multitude of other symptoms that plague patients with cancer and brain metastases (supportive care). Although RT itself causes an increase in ICP, together with certain phrmacological agents, it also diminishes the cause of increased ICP.Keywords: Increased ICP, brain metastasis, radiotherapy, supportive careTurkiye Klinikleri J Surg Med Sci 2006, 2(33):6-10
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